Liver cirrhosis remains one of the leading causes of mortality and disability among patients with gastrointestinal diseases. A significant proportion of cases are diagnosed at late stages, limiting effective treatment options and worsening the prognosis. The increasing incidence and high complication rate necessitate strengthening the primary care role in early detection, monitoring, and prevention of liver cirrhosis progression.

These guidelines systematize modern approaches to the management of patients with liver cirrhosis. The document presents diagnostic criteria, including clinical and paraclinical signs, as well as principles for a comprehensive patient assessment. A detailed follow-up algorithm is outlined, emphasizing the assessment of the patient's condition and the early decompensation detection. Particular attention is paid to the diagnosis and monitoring of complications (portal hypertension, ascites, hepatic encephalopathy, etc.), interpretation of laboratory parameters, and the use of diagnostic methods. The principles of non-drug and drug therapy, preventive counseling, vaccination, and referral criteria for hospitalization and liver transplantation are discussed.

This document is intended for general practitioners, gastroenterologists, and other primary care specialists involved in providing care to patients with liver cirrhosis.

Atherosclerosis of the extracranial carotid artery is one of the main causes of cerebrovascular accidents. Considering the high medical and social significance of the consequences of cerebrovascular accidents, in particular ischemic stroke, and the relevance of an interdisciplinary approach to the optimal management of patients with carotid artery atherosclerosis, these guidelines describes the management of patients with carotid artery occlusion and stenosis by a primary care physician.

These guidelines allow the practitioner to make informed clinical decisions when conducting clinical observation.

The guidelines are, first of all, intended for primary care physicians, general practitioners, as well as for nurses working with these doctors, for paramedics at primary care facilities performing the doctor functions within follow-up monitoring. These guidelines should be of no less interest to public health physicians, heads of primary care facilities and their departments.

The high and steadily increasing prevalence of chronic kidney disease (CKD) is a significant medical and social problem. CKD complications significantly reduce quality of life and increase the risk of disability, hospitalization, and death. Timely identification and correction of modifiable risk factors for CKD progression underpins secondary prevention measures.

These guidelines describe the management of follow-up monitoring for CKD patients by a general practitioner and incorporate modern approaches to diagnosing disease severity and complications (clinical and paraclinical methods), as well as disease treatment and complication prevention. Application of these guidelines will enable physicians to make informed clinical decisions based on the presented diagnostic algorithm (examinations, consultations). These guidelines are intended for general practitioners, family doctors, and for nursing staff working with these physicians, for paramedics performing the doctor functions of managing follow-up monitoring. These guidelines are also intended for healthcare executives, heads of primary care facilities, and their departments.

These guidelines describe the management of follow-up monitoring for patients with chronic pancreatitis by a general practitioner and outline modern approaches to diagnosis, including clinical, laboratory, and imaging methods, treatment, and the prevention of complications.

Using the follow-up care (examination, consultation) algorithm presented in these guidelines will enable physicians providing follow-up monitoring for patients with chronic pancreatitis to make informed clinical decisions.

These guidelines are intended for general practitioners, family doctors, and for nursing staff working with these physicians, for paramedics performing the doctor functions of managing follow-up monitoring. These guidelines are also intended for healthcare executives and heads of primary care facilities.

Crohn's disease is a chronic, relapsing gastrointestinal disorder of unknown etiology, characterized by transmural, segmental, granulomatous inflammation with the development of local and systemic complications. The disease progresses with alternating periods of remission and exacerbations and may be accompanied by the development of strictures, fistulas, abscesses, intestinal bleeding, extraintestinal manifestations, decreased quality of life, and the risk of disability.

These guidelines address the management of follow-up care for patients with Crohn's disease in primary care. The document presents the basic principles of patient registration for follow-up monitoring, the frequency of follow-up visits, and an algorithm for assessing complaints, medical history, physical and paraclinical examination methods. Particular attention is paid to monitoring disease activity, treatment efficacy and safety, assessing the achievement of health targets, promptly identifying unfavorable prognostic factors and indications for hospitalization, as well as preventive measures. Follow-up care is considered a key element of proactive patient management aimed at maintaining steroid-free remission, preventing complications, reducing the hospitalization rate, and improving long-term clinical outcomes.

These guidelines are intended for internists, primary care physicians, general practitioners, and paramedics performing the doctor’s functions. They may also be useful for gastroenterologists, proctologists, healthcare executives, and other specialists involved in the management and monitoring of patients with Crohn's disease.

These guidelines address the management of outpatient follow-up care for adult patients with ulcerative colitis by a primary care physician. The document was developed taking into account current clinical guidelines for ulcerative colitis and current regulatory documents.

The guidelines provide basic information about the disease, including the definition of ulcerative colitis, clinical course, epidemiological data, and diagnosis criteria. Particular attention is paid to the algorithm for outpatient follow-up care (complaint and history collection, physical examination, paraclinical investigations, criteria for achieving health goals, and indications for referral to specialist physicians). Diet therapy, nutritional support, and surgical treatment are discussed, as well as the prevention of complications and colorectal cancer.

The guidelines are intended for internists, general practitioners, gastroenterologists, proctologists, and other specialists involved in the care of patients with ulcerative colitis. Their use is aimed at improving the quality of follow-up care and ensuring continuity between specialists.

Interstitial lung diseases are a heterogeneous group of pathologies, the most common of which is idiopathic pulmonary fibrosis. The causes of interstitial diseases often remain unknown, but their pathogenesis is based on the gradual replacement of normal lung tissue with fibrous tissue. More than half of patients with interstitial lung diseases experience fibrosis progression, worsening symptoms, and the onset of respiratory failure within 2 years of diagnosis. Early diagnosis and timely follow-up are the primary means of disease management, particularly for idiopathic pulmonary fibrosis. This includes slowing disease progression, reducing the frequency and severity of exacerbations, and reducing the risk of developing and progressing different acute and chronic conditions that can affect respiratory symptoms and the prognosis of interstitial lung diseases.

These guidelines are intended for primary care physicians, general practitioners, nurses working with these physicians, and paramedics at primary care facilities performing the doctor functions, including conducting outpatient follow-up. These guidelines are also intended for specialists such as pulmonologists, allergists/ immunologists, and other specialists involved in the care of patients with interstitial lung diseases. In addition, these guidelines are intended for heads of healthcare facilities (or its divisions) providing primary care, as well as students, residents, and postgraduate students at medical and pharmaceutical educational institutions.

Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders characterized by chronic recurrent symptoms, abdominal pain, irregular stool frequency and consistency, flatulence, and a significant impact on patients' quality of life. IBS is associated with decreased productivity, frequent health encounters, diagnostic and treatment costs, and the need for long-term follow-up. The development of guidelines is relevant to the need to standardize approaches to outpatient management of IBS patients, improve treatment effectiveness, promptly rule out organic pathology, and ensure continuity of care between general practitioners, gastroenterologists, and other specialists.

These guidelines address the management of adult patients with IBS in primary care. The document presents diagnostic criteria, including the Rome IV and V criteria, a dynamic monitoring algorithm, a list of alarm symptoms, approaches to laboratory and imaging diagnostics, disease severity assessment, diagnosis formulation, determining indications for hospitalization, and referral to specialist physicians. Particular attention is paid to non-drug and drug therapy, preventive counseling, assessing treatment adherence, informing the patient, and preparing medical documentation.

These guidelines are intended for internists, general practitioners, gastroenterologists, primary care specialists, and healthcare providers involved in the management and dynamic monitoring of patients with IBS.

These guidelines contain information on the theoretical foundations of prostate cancer screening, regulatory acts governing the management of prostate cancer screening of specific adult population groups, the specifics of interpreting the results of laboratory and imaging examinations during prostate cancer screening, and patient routing algorithms.

These guidelines have been developed for the heads of health facilities providing primary healthcare, including primary care physicians, general practitioners, urologists, and specialists with secondary medical education who are directly involved in outpatient screening of specific adult population groups.

These guidelines were developed to provide organizational and methodological support for the implementation of the "Regional Model for Managing Primary Health Care for Patients with Prediabetes" program in Russian regions. The document aims to develop a unified approach to the early detection of prediabetes, patient referral, follow-up care, preventive counseling, training of healthcare workers, and evaluation of the effectiveness of interventions at the regional and institutional levels. The guidelines present the regulatory, organizational, medical, social, and educational components of the program, as well as propose a structure for the regional program's data sheet, a roadmap for its implementation, algorithms for administrative and managerial decisions, and approaches to registering patients with prediabetes. Particular attention is given to the system of performance criteria and indicators, including the detection of prediabetes during preventive measures, coverage of follow-up monitoring and preventive counseling, the proportion of trained healthcare workers, and the changes of type 2 diabetes cases among patients monitored for prediabetes. The proposed methodologies for calculating indicators allow for standardized monitoring of program implementation, comparative evaluation of health facilities, and the use of the obtained data for management decision-making. These guidelines are intended for specialists from executive authorities of the constituent entities of the Russian Federation in the field of healthcare, territorial compulsory health insurance funds, medical insurance organizations, heads of healthcare organizations, and specialists involved in providing primary healthcare to patients with prediabetes.

These guidelines for the development, implementation, and evaluation of the regional program "Health Promotion and the Creation of a Health-Saving Environment" were prepared as part of the Federal Project "Health for Everyone" of the National Project "Long and Active Life." They are based on an analysis and evaluation of existing regional public health promotion programs and present modern, evidence-based approaches and practical recommendations for implementing a program aimed at promoting health and creating a health-saving environment at the regional level.

These guidelines have been prepared to provide organizational, methodological, and practical assistance to specialists at Public Health and Prevention Centers, representatives of executive authorities of the Russian regions, and other stakeholders involved in the development and implementation of regional health promotion programs and the creation of a health-saving environment.

Chronic kidney disease (CKD) develops as a result of a gradual and irreversible decline in kidney function caused by various factors. Patients with end-stage renal failure undergo long-term or lifelong renal replacement therapy — chronic hemodialysis. Patients on chronic hemodialysis are at high risk, the main ones being cardiovascular events, strokes, infections associated with vascular access (fistula) or peritoneal catheters, as well as anemia, mineral metabolism disorders, and intradialytic hypotension.

Educating patients on chronic hemodialysis through patient "schools" plays an important role in improving their quality of life and reducing the risk of complications associated with both the hemodialysis process itself and end-stage CKD. The guidelines for managing "school" for patients on chronic hemodialysis contain general information about the disease, organize and conduction of patient "schools", recommended topics and lesson content, and tests for assessing patient knowledge.

The guidelines are intended for specialists who meet the qualification requirements for medical and pharmaceutical workers with secondary vocational education in General Medicine or Nursing, as well as for primary care physicians involved in conducting patient "schools".